SCHEMBL20019686

SCHEMBL20019686

CN1C(=O)C(Cc2c[nH]cn2)N(S(C)(=O)=O)C12CCN(C(=O)OC(C)(C)C)CC2

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13363631 0.74 GPR119 (0.39) GPR119
SCHEMBL25631401 0.74 FAAH (0.47) GPR119
SCHEMBL12656247 0.74 DDB1 (0.38) GPR119
SCHEMBL12626394 0.72 GPR119 (0.36) GPR119
SCHEMBL12626407 0.70 GPR119 (0.40) GPR119
SCHEMBL28709578 0.69 CHRM2 (0.44) GPR119
SCHEMBL4832554 0.69 DTYMK (0.43) GPR119
SCHEMBL6197983 0.68 BACE1 (0.40) GPR119
SCHEMBL948492 0.67 L3MBTL1 (0.48) GPR119
SCHEMBL948089 0.67 SYK (0.41) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2918587-B1 Filamin A binding compounds and their use as anti-inflammatory and analgesic agents PAIN THERAPEUTICS INC (US) 2018-04-04 EP disclosed