Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323941 | 0.84 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL20020768 | 0.82 | CNR1 (0.45) | KDM4EALDH1A1POLBHPGDPTGDR2 | |
| SCHEMBL3297610 | 0.80 | KDM4E (0.54) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL20021110 | 0.80 | KDM4E (0.45) | KDM4EMEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL20021165 | 0.79 | KDM4E (0.52) | KDM4EMEN1KMT2APTGDR2SMN1; SMN2 | |
| SCHEMBL3303954 | 0.79 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL243290 | 0.79 | PSIP1 (0.47) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL20021122 | 0.78 | KDM4E (0.52) | KDM4EMEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL27910430 | 0.78 | MEN1 (0.36) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL3303958 | 0.77 | KMT2A (0.49) | KDM4EMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588455-B1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |