Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1544448 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL14076990 | 0.77 | RAB9A (0.54) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL22018553 | 0.72 | USP2 (0.79) | ALDH1A1HPGDHSD17B10TP53MEN1 | |
| SCHEMBL1545186 | 0.71 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL14077056 | 0.71 | TSHR (0.59) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL8625712 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL4208837 | 0.70 | ALDH1A1 (0.78) | ALDH1A1HPGDHSD17B10TP53MEN1 | |
| SCHEMBL1544366 | 0.67 | RAB9A (0.51) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL20021735 | 0.66 | KMT2A (0.52) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL8628320 | 0.65 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11856955-B2 | Binary compositions as disruptors of Orco-mediated odorant sensing | VANDERBILT UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| US-20180092359-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | VANDERBILT UNIVERSITY | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11856955-B2 | Binary compositions as disruptors of Orco-mediated odorant sensing | OR51E2, OR10J3, ORC3 | ALDH1A1 2481/4885KDM4E 3247/4885HPGD 4619/4885 |
| US-20180092359-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | OR51E2, OR10J3, ORC3 | ALDH1A1 2668/4885KDM4E 3295/4885HPGD 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.