Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20022802 | 0.81 | MKNK1 (0.38) | ALDH1A1RAB9ASMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL20028553 | 0.77 | BRD4 (0.38) | ALDH1A1CREBBPSCDSCD5BRD4 | |
| SCHEMBL20022788 | 0.74 | ALDH1A1 (0.39) | ALDH1A1RAB9ASMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL20022798 | 0.74 | GRIN2B (0.33) | RAB9ASMN1; SMN2MKNK1MKNK2SLC6A4 | |
| SCHEMBL20022803 | 0.73 | BRD4 (0.31) | MKNK1MKNK2SLC6A4SLC6A3GRIN2B | |
| SCHEMBL18209870 | 0.72 | MEN1 (0.44) | RAB9ASMN1; SMN2CREBBPSLC6A4KMT2A | |
| SCHEMBL20022781 | 0.70 | SMN1; SMN2 (0.42) | ALDH1A1RAB9ASMN1; SMN2SLC6A4SLC6A3 | |
| SCHEMBL15164429 | 0.69 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2SLC6A4SLC6A3 | |
| SCHEMBL30546565 | 0.66 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2SLC6A4SLC6A3 | |
| SCHEMBL9919107 | 0.64 | BRD4 (0.59) | ALDH1A1CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093985-A1 | Heterocyclic Compounds and Their Use in Preventing or Treating Bacterial Infections | MUTABILIS (FR) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093985-A1 | Heterocyclic Compounds and Their Use in Preventing or Treating Bacterial Infections | NQO1, PEPD, LCT | ALDH1A1 830/4885RAB9A 1331/4885SMN1; SMN2 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.