Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18209824 | 0.81 | ALDH1A1 (0.40) | SMN1; SMN2TP53ALDH1A1RAB9AFAAH | |
| SCHEMBL20022782 | 0.80 | ALDH1A1 (0.37) | SMN1; SMN2KDM4ETP53L3MBTL1ALDH1A1 | |
| SCHEMBL20028325 | 0.77 | SMO (0.36) | SMOFAAHHPGDSKMT2A | |
| SCHEMBL20022788 | 0.74 | ALDH1A1 (0.39) | SMN1; SMN2KDM4ETP53L3MBTL1ALDH1A1 | |
| SCHEMBL18209719 | 0.72 | FAAH (0.47) | SMN1; SMN2NPC1RAB9AFAAHKMT2A | |
| SCHEMBL20022779 | 0.71 | SMO (0.32) | SMOFAAHKMT2A | |
| SCHEMBL20022797 | 0.70 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1CARM1RAB9AKMT2A | |
| SCHEMBL15164429 | 0.69 | ALDH1A1 (0.57) | SMN1; SMN2KDM4ETP53L3MBTL1ALDH1A1 | |
| SCHEMBL30546565 | 0.66 | ALDH1A1 (0.57) | SMN1; SMN2KDM4EALDH1A1CARM1RAB9A | |
| SCHEMBL4875267 | 0.64 | ALDH1A1 (0.79) | SMN1; SMN2KDM4EALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093985-A1 | Heterocyclic Compounds and Their Use in Preventing or Treating Bacterial Infections | MUTABILIS (FR) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093985-A1 | Heterocyclic Compounds and Their Use in Preventing or Treating Bacterial Infections | NQO1, PEPD, LCT | SMN1; SMN2 3965/4885KDM4E 3033/4885TP53 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.