SCHEMBL20022971

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8181400	0.87	ALDH1A1 (0.56)	ALDH1A1CYP3A4CYP1A2CYP2C19NPC1
	SCHEMBL8736580	0.79	ALDH1A1 (0.68)	ALDH1A1CYP3A4CYP1A2CYP2C19NPC1
	SCHEMBL7990509	0.78	ALDH1A1 (0.59)	ALDH1A1CYP3A4CYP1A2CYP2C19NPC1
	SCHEMBL2461730	0.78	CYP3A4 (1.00)	ALDH1A1CYP3A4CYP1A2CYP2C19NPC1
	SCHEMBL31114377	0.78	CYP3A4 (1.00)	ALDH1A1CYP3A4CYP1A2CYP2C19NPC1
	SCHEMBL31171631	0.78	ACE (0.58)	ALDH1A1CYP3A4NPC1RAB9ATSHR
	SCHEMBL31171638	0.78	ACE (0.58)	ALDH1A1CYP3A4NPC1RAB9ATSHR
	SCHEMBL7636977	0.78	ALDH1A1 (0.66)	ALDH1A1HTT
	SCHEMBL6800842	0.77	ACE (0.61)	ALDH1A1CYP3A4CYP1A2CYP2C19NPC1
	SCHEMBL27969666	0.76	CYP3A4 (0.62)	ALDH1A1CYP3A4CYP1A2CYP2C19NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.