Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 3/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938275 | 0.85 | CYP3A4 (0.52) | ALDH1A1RAB9ANPC1TSHRSMN1; SMN2 | |
| SCHEMBL8181400 | 0.81 | ALDH1A1 (0.56) | ACEALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL20022971 | 0.77 | ALDH1A1 (0.63) | ACEALDH1A1RAB9ANPC1TSHR | |
| Fasidotrilat SCHEMBL29595981 | 0.76 | ACE (1.00) | ACEALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL8805246 | 0.76 | MAOB (0.61) | ACEALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL8805245 | 0.76 | MAOB (0.61) | ACEALDH1A1RAB9ANPC1MAPT | |
| Fasidotril SCHEMBL49006 | 0.75 | ACE (0.88) | ACEALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL1650036 | 0.75 | ACE (0.58) | ACEALDH1A1RAB9ANPC1TSHR | |
| Fasidotril SCHEMBL7301419 | 0.75 | ACE (0.88) | ACEALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL6395296 | 0.74 | MEN1 (0.56) | ACEALDH1A1RAB9ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835851-B2 | Reacting said alpha - substituted acrylic acid with an chloro acid so as to obtain an acid chloride, now reacting acid chloride thus obtained with an amino ester in presence of an organic base, to acheive coupling | BIOPROJET (FR) | 2004-12-28 | — | — | US | disclosed |
| US-20020055645-A1 | Process for synthesizing N-(mercaptoacyl) amino acid derivatives from alpha-substituted acrylic acids | BIOPROJET (FR) | 2002-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055645-A1 | Process for synthesizing N-(mercaptoacyl) amino acid derivatives from alpha-substituted acrylic acids | TST, ASS1, SULT1A1 | ACE 921/4885ALDH1A1 102/4885RAB9A 2766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.