Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.48 |
| ▸ | RAB9A | P51151 | 11/20 | 0.48 |
| ▸ | NPC1 | O15118 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022340 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2TP53KDM4ERAB9ANPC1 | |
| SCHEMBL12832006 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53KDM4ERAB9ANPC1 | |
| SCHEMBL26611347 | 0.78 | KDM4E (0.56) | SMN1; SMN2TP53KDM4ERAB9ANPC1 | |
| SCHEMBL18793697 | 0.76 | RAB9A (0.46) | SMN1; SMN2TP53KDM4ERAB9ANPC1 | |
| SCHEMBL434154 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2TP53KDM4ERAB9ANPC1 | |
| SCHEMBL26612297 | 0.74 | KDM4E (0.62) | SMN1; SMN2TP53KDM4ERAB9ANPC1 | |
| SCHEMBL26699228 | 0.73 | KDM4E (0.54) | SMN1; SMN2TP53KDM4ERAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6544490 | 0.73 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53KDM4ERAB9ANPC1 | |
| SCHEMBL18569907 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2TP53KDM4ERAB9ANPC1 | |
| SCHEMBL8811617 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2TP53KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109996546-B | P2X 3 And/or P2X 2/3 Compounds and methods | 阿沙纳生物科学公司 | 2023-06-27 | — | — | CN | claimed |
| US-20180093991-A1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ASANA BIOSCIENCES, LLC | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093991-A1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | P2RX3, P2RX6, P2RX2 | SMN1; SMN2 487/4885TP53 2907/4885KDM4E 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.