Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224448 | 0.85 | CLCN2 (0.50) | CLCN2HMGB1GABRA1GABRB2FOLH1 | |
| SCHEMBL27494534 | 0.84 | ALDH1A1 (0.52) | HMGB1ALDH1A1ALOX15KDM4EHPGD | |
| SCHEMBL7111511 | 0.84 | BID (0.52) | ALOX15KDM4EHSD17B10CA12CA9 | |
| SCHEMBL16952548 | 0.83 | GABRA1 (0.43) | CLCN2GABRA1GABRB2ALDH1A1HTT | |
| SCHEMBL16960470 | 0.80 | GABRA1 (0.41) | CLCN2GABRA1GABRB2ALDH1A1HTT | |
| SCHEMBL1363486 | 0.80 | GABRA1 (0.50) | GABRA1GABRB2TDP1 | |
| SCHEMBL31338864 | 0.79 | ALDH1A1 (0.55) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL357340 | 0.79 | ALDH1A1 (0.55) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL16952121 | 0.79 | GABRA1 (0.39) | CLCN2GABRA1GABRB2HTTKMT2A | |
| SCHEMBL27707631 | 0.78 | CLCN2 (0.44) | CLCN2HMGB1GABRA1GABRB2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516426-A1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | Bayer CropScience AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011076699-A1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-06-30 | — | — | WO | disclosed |
| EP-0126231-B1 | VINYLPHENYL BENZIMIDAZOLE DERIVATIVES, THEIR POLYMERS, THEIR PREPARATION AND USE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-12-20 | — | — | EP | disclosed |
| US-4791183-A | 1,2-DIHALOETHYL STYRENES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-12-13 | — | — | US | disclosed |
| US-4533678-A | BENZIMIDAZOLYLSTYRENE POLYMERS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0126231-A2 | Vinylphenyl benzimidazole derivatives, their polymers, their preparation and use | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-11-28 | — | — | EP | disclosed |