Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20028695 | 0.87 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL18630525 | 0.86 | BRD4 (0.53) | — | |
| SCHEMBL719300 | 0.84 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL3895476 | 0.84 | TSHR (0.66) | TSHRSMN1; SMN2ALDH1A1HTTMMP13 | |
| SCHEMBL27508531 | 0.81 | TSHR (0.51) | TSHRSMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL6228914 | 0.80 | LMNA (0.58) | TSHRSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL8750992 | 0.78 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1HTTMMP13 | |
| SCHEMBL8257957 | 0.78 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1MMP13HPGD | |
| SCHEMBL13450827 | 0.76 | TSHR (0.57) | TSHRSMN1; SMN2ALDH1A1HTTMMP13 | |
| SCHEMBL13037029 | 0.76 | TSHR (0.57) | TSHRSMN1; SMN2ALDH1A1HTTMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064119-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |