Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616909 | 0.85 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HSD17B10HPGDKMT2A | |
| SCHEMBL7753044 | 0.80 | POLB (0.39) | ALDH1A1SMN1; SMN2HSD17B10HPGDKMT2A | |
| SCHEMBL177981 | 0.79 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HSD17B10HPGDKMT2A | |
| SCHEMBL5162362 | 0.78 | HPGD (0.38) | ALDH1A1SMN1; SMN2HSD17B10HPGDKMT2A | |
| SCHEMBL6687766 | 0.76 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HSD17B10HPGDKMT2A | |
| SCHEMBL177980 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HSD17B10HPGDKMT2A | |
| SCHEMBL2002797 | 0.71 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HSD17B10HPGDKMT2A | |
| SCHEMBL28380361 | 0.71 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HSD17B10KMT2AMAPT | |
| SCHEMBL616908 | 0.71 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HSD17B10HPGDKMT2A | |
| SCHEMBL21768790 | 0.71 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HSD17B10HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175701-A1 | OVR110 ANTIBODY COMPOSITIONS AND METHODS OF USE | DIADEXUS, INC. (US) | 2015-06-25 | — | — | US | disclosed |
| US-8906369-B2 | Ovr110 antibody compositions and methods of use | DIADEXUS, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20130232589-A1 | OVR110 ANTIBODY COMPOSITIONS AND METHODS OF USE | DIADEXUS, INC. (US) | 2013-09-05 | — | — | US | disclosed |
| US-8444971-B2 | OVR110 antibody compositions and methods of use | DIADEXUS, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-8354508-B2 | PRO115 antibody compositions and methods of use | DIADEXUS, INC. (US) | 2013-01-15 | — | — | US | disclosed |
| US-8207311-B2 | Ovr115 antibody compositions and methods of use | DIADEXUS, INC. (US) | 2012-06-26 | — | — | US | disclosed |
| US-8148093-B2 | Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk | DIADEXUS, INC. | 2012-04-03 | — | — | US | disclosed |
| EP-1633784-B1 | OVR110 ANTIBODY COMPOSITIONS AND METHODS OF USE | DIADEXUS INC (US) | 2011-07-13 | — | — | EP | disclosed |
| US-20110159516-A1 | PCan065 Antibody Compositions and Methods of Use | DIADEXUS, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| US-7964195-B2 | Using immunoglobulin which preferentially binds cancer specific antigen (OVR110) as treatment for head and neck or endometrial cancer | DIADEXUS, INC. | 2011-06-21 | — | — | US | disclosed |
| US-20100150907-A1 | PRO115 ANTIBODY COMPOSITIONS AND METHODS OF USE | DIADEXUS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100136009-A1 | OVR110 Antibody Compositions and Methods of Use | DIAZYME LABORATORIES, INC. | 2010-06-03 | — | — | US | disclosed |
| US-20070104647-A1 | Ovr115 antibody compositions and methods of use | DIAZYME LABORATORIES, INC. | 2007-05-10 | — | — | US | disclosed |