SCHEMBL616909

SCHEMBL616909

O=C(O)CC(Sc1ccccn1)N1C(=O)CCC1=O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
HSD17B10 Q99714 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HPGD P15428 2/20 0.41
PKM P14618 2/20 0.40
KMT2A Q03164 5/20 0.38
MAPT P10636 3/20 0.38
ATM Q13315 1/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
POLB P06746 2/20 0.37
SLC1A2 P43004 1/20 0.36
KDM4E B2RXH2 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753044 0.90 POLB (0.39) ALDH1A1HSD17B10SMN1; SMN2HPGDPKM
SCHEMBL6687766 0.87 ALDH1A1 (0.42) ALDH1A1HSD17B10SMN1; SMN2HPGDPKM
SCHEMBL2002799 0.85 ALDH1A1 (0.46) ALDH1A1HSD17B10SMN1; SMN2HPGDPKM
SCHEMBL10980060 0.83 KMT2A (0.38) ALDH1A1SMN1; SMN2HPGDPKMKMT2A
SCHEMBL5162362 0.82 HPGD (0.38) ALDH1A1HSD17B10SMN1; SMN2HPGDPKM
SCHEMBL8082242 0.76 EHMT2 (0.38) ALDH1A1HSD17B10SMN1; SMN2HPGDPKM
SCHEMBL9398036 0.75 ITGB3 (0.40) ALDH1A1KMT2AATMMEN1POLB
SCHEMBL177980 0.75 ALDH1A1 (0.48) ALDH1A1HSD17B10SMN1; SMN2HPGDPKM
SCHEMBL616908 0.75 ALDH1A1 (0.54) ALDH1A1HSD17B10SMN1; SMN2HPGDPKM
SCHEMBL7421417 0.73 SMN1; SMN2 (0.55) ALDH1A1HSD17B10SMN1; SMN2HPGDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250281628-A1 COMPOSITE NANOPARTICULATE MINERALIZED COLLAGEN GLYCOSAMINOGLYCAN MATERIALS WITH TIME RELEASE ANTI-RESORPTIVE FACTORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-09-11 US claimed
EP-4392087-A2 COMPOSITE NANOPARTICULATE MINERALIZED COLLAGEN GLYCOSAMINOGLYCAN MATERIALS WITH TIME RELEASE ANTI-RESORPTIVE FACTORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-03 EP claimed
WO-2023028082-A2 COMPOSITE NANOPARTICULATE MINERALIZED COLLAGEN GLYCOSAMINOGLYCAN MATERIALS WITH TIME RELEASE ANTI-RESORPTIVE FACTORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-02 WO claimed
WO-2009077438-A1 METHOD FOR PREPARING PROTEIN CONJUGATES GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) 2009-06-25 WO claimed
EP-1578450-A4 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRAL (AU) 2009-06-17 EP claimed
EP-1740954-A1 MASS SPECTROMETRY OF ANTIBODY CONJUGATES Kadkhodayan, Miryam (US) 2007-01-10 EP claimed
US-20060127310-A1 Amplification of biotin-mediated targeting ACCESS PHARMACEUTICALS AUSTRALIA PTY LTD. 2006-06-15 US claimed
WO-2005101017-A1 MASS SPECTROMETRY OF ANTIBODY CONJUGATES GENENTECH, INC. (US) 2005-10-27 WO claimed
EP-1578450-A1 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING Access Pharmaceuticals Australia Pty Ltd (AU) 2005-09-28 EP claimed
WO-2005086775-A2 LUMEN-EXPOSED MOLECULES AND METHODS FOR TARGETED DELIVERY UTAH VENTURES II, L.P. (US) 2005-09-22 WO claimed
US-20040146516-A1 Lumen-exposed molecules and methods for targeted delivery UTAH VENTURES II L.P. 2004-07-29 US claimed
EP-1206251-A4 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES ACCESS PHARMACEUTICALS AUSTRAL (AU) 2004-06-30 EP claimed
WO-2004045647-A1 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRALIA PTY LTD (AU) 2004-06-03 WO claimed
EP-1206251-A1 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES BIOTECH AUSTRALIA PTY. LIMITED (AU) 2002-05-22 EP claimed
WO-2000066090-A1 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES BIOTECH AUSTRALIA PTY LIMITED (AU) 2000-11-09 WO claimed
EP-0308936-B1 Antibody heteroconjugates for the killing of HIV-infected cells BRISTOL MYERS SQUIBB CO (US) 1994-07-06 EP claimed
JP-2173000-A None JP disclosed
JP-8053499-A None JP disclosed
EP-0040365-B1 AN ASSAYING METHOD INVOLVING BIOSPECIFIC AFFINITY REACTIONS PHARMACIA DIAGNOSTICS AB (SE) 1985-08-21 EP disclosed
US-4507234-A Conjugate having cytotoxicity and process for the preparation thereof TEIJIN LIMITED (JP) 1985-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060127310-A1 Amplification of biotin-mediated targeting BTD, HLCS, SLC1A5 ALDH1A1 1010/4885HSD17B10 4046/4885SMN1; SMN2 4527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.