Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 4/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20028096 | 0.80 | CYP19A1 (0.54) | ALDH1A1MAPTGAATSHRCYP1A2 | |
| SCHEMBL3492608 | 0.74 | MEN1 (0.51) | ALDH1A1KDM4ETSHRLMNAKDM5A | |
| SCHEMBL5794357 | 0.74 | PKM (0.52) | ALDH1A1PTGS2GAAPKMTSHR | |
| SCHEMBL8235626 | 0.74 | MEN1 (0.51) | ALDH1A1KDM4ETSHRLMNAKDM5A | |
| SCHEMBL1009513 | 0.73 | NSD3 (0.83) | NSD3KDM4CKDM2BPTGS2TSHR | |
| SCHEMBL12926032 | 0.73 | NSD3 (0.56) | NSD3MAPTKDM4CKDM2BTSHR | |
| SCHEMBL29874438 | 0.72 | NSD3 (0.80) | NSD3KDM4CKDM2BPTGS2TSHR | |
| SCHEMBL27216970 | 0.72 | NSD3 (0.54) | NSD3PTGS2TSHRCYP1A2CA1 | |
| SCHEMBL18721829 | 0.72 | NSD3 (0.54) | NSD3PTGS2TSHRCYP1A2CYP2C19 | |
| SCHEMBL17928542 | 0.72 | NSD3 (0.54) | NSD3ALDH1A1MAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | BLADE THERAPEUTICS, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| WO-2018064119-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | CAPNS1, CAPN9, CAPN1 | NSD3 3321/4885ALDH1A1 4193/4885MAPT 562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.