Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
| ▸ | EED | O75530 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22080349 | 0.84 | CYP19A1 (0.53) | CYP19A1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL22027566 | 0.83 | ALDH1A1 (0.53) | CYP19A1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20028090 | 0.80 | NSD3 (0.50) | ALDH1A1CYP2C9CYP2C19MAPTCA1 | |
| SCHEMBL3491424 | 0.79 | CYP19A1 (0.48) | CYP19A1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8236392 | 0.79 | CYP19A1 (0.48) | CYP19A1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6274152 | 0.78 | GABRA2 (0.59) | CYP19A1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3495474 | 0.77 | CYP19A1 (0.46) | CYP19A1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20027816 | 0.77 | CYP19A1 (0.68) | CYP19A1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20028095 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL10057637 | 0.77 | ALDH1A1 (0.55) | CYP19A1ALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | BLADE THERAPEUTICS, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| WO-2018064119-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | CAPNS1, CAPN9, CAPN1 | CYP19A1 4551/4885ALDH1A1 4193/4885CYP3A4 4746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.