Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 9/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.37 |
| ▸ | HPGDS | O60760 | 4/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20028429 | 0.89 | PYGL (0.42) | PYGLCCR1HPGDSCAPN1 | |
| SCHEMBL20028423 | 0.86 | CDC7 (0.42) | PYGLCCR1HPGDS | |
| SCHEMBL21854344 | 0.84 | CAPN1 (0.49) | CAPN1 | |
| SCHEMBL22886609 | 0.83 | PYGL (0.45) | PYGLCCR1HPGDS | |
| SCHEMBL22886536 | 0.82 | CAPN1 (0.40) | MAPK14CAPN1 | |
| SCHEMBL22886851 | 0.79 | CAPN1 (0.38) | CAPN1 | |
| SCHEMBL22895963 | 0.78 | CAPN1 (0.42) | CAPN1 | |
| SCHEMBL20028427 | 0.77 | PYGL (0.41) | PYGLCCR1HPGDS | |
| SCHEMBL22896738 | 0.76 | CAPN1 (0.43) | CAPN1 | |
| SCHEMBL22886430 | 0.75 | PYGL (0.41) | PYGLCCR1HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064119-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |