Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 5/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.37 |
| ▸ | HPGDS | O60760 | 4/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20028424 | 0.89 | PYGL (0.40) | PYGLCCR1CAPN1HPGDS | |
| SCHEMBL22886609 | 0.86 | PYGL (0.45) | PYGLCCR1HPGDSCTSD | |
| SCHEMBL20028423 | 0.84 | CDC7 (0.42) | PYGLCCR1HPGDSCTSD | |
| SCHEMBL21854095 | 0.83 | CAPN1 (0.54) | CAPN1 | |
| SCHEMBL22886508 | 0.81 | CAPN1 (0.45) | CAPN1KMT2A | |
| SCHEMBL20028427 | 0.80 | PYGL (0.41) | PYGLCCR1HPGDS | |
| SCHEMBL22886566 | 0.78 | CAPN1 (0.43) | CAPN1KMT2A | |
| SCHEMBL22896974 | 0.78 | CAPN1 (0.48) | CAPN1 | |
| SCHEMBL22896540 | 0.78 | CAPN1 (0.44) | CAPN1 | |
| SCHEMBL22886430 | 0.77 | PYGL (0.41) | PYGLCCR1HPGDSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064119-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |