⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5430626 | 0.95 | PRMT6 (0.58) | — | |
| SCHEMBL2003710 | 0.93 | PRMT6 (0.56) | — | |
| SCHEMBL13178507 | 0.93 | PRMT6 (0.56) | — | |
| SCHEMBL4783223 | 0.90 | ACE2 (0.54) | — | |
| SCHEMBL13660816 | 0.89 | PRMT6 (0.43) | — | |
| SCHEMBL19071988 | 0.85 | ACE2 (0.56) | — | |
| SCHEMBL7730804 | 0.83 | ACE2 (0.48) | — | |
| SCHEMBL10282545 | 0.83 | ACE2 (0.48) | — | |
| SCHEMBL24971199 | 0.82 | CXCR4 (0.58) | — | |
| SCHEMBL6733235 | 0.81 | CARM1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851073-B2 | Protein tyrosine phosphatase inhibitors and methods of use thereof | ABBVIE INC. (US) | 2020-12-01 | — | — | US | disclosed |
| WO-2018064557-A1 | SUBSTITUTED FUSED BI- OR TRI- HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS | Epizyme, Inc. (US) | 2018-04-05 | — | — | WO | disclosed |