Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730804 | 0.92 | ACE2 (0.48) | PRMT6CARM1PRMT8ACE2KDM1A | |
| SCHEMBL20028835 | 0.89 | — | — | |
| SCHEMBL21367124 | 0.88 | ACE2 (0.50) | PRMT6CARM1PRMT8SIGMAR1ACE2 | |
| SCHEMBL5430626 | 0.85 | PRMT6 (0.58) | PRMT6CARM1PRMT8SIGMAR1ACE2 | |
| SCHEMBL4783223 | 0.85 | ACE2 (0.54) | PRMT6CARM1PRMT8SIGMAR1ACE2 | |
| SCHEMBL13178507 | 0.83 | PRMT6 (0.56) | PRMT6CARM1PRMT8SIGMAR1ACE2 | |
| SCHEMBL2003710 | 0.83 | PRMT6 (0.56) | PRMT6CARM1PRMT8SIGMAR1ACE2 | |
| SCHEMBL19071988 | 0.81 | ACE2 (0.56) | PRMT6CARM1PRMT8SIGMAR1ACE2 | |
| SCHEMBL4395015 | 0.80 | ACE2 (0.61) | PRMT6CARM1PRMT8SIGMAR1ACE2 | |
| SCHEMBL22416471 | 0.79 | ACE2 (0.40) | PRMT6CARM1PRMT8ACE2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |