Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19071988 | 0.95 | ACE2 (0.56) | ACE2PRMT6CARM1PRMT8CYP2C19 | |
| SCHEMBL10282545 | 0.93 | ACE2 (0.48) | ACE2PRMT6CARM1PRMT8CYP2C19 | |
| SCHEMBL7730804 | 0.93 | ACE2 (0.48) | ACE2PRMT6CARM1PRMT8CYP2C19 | |
| SCHEMBL25737704 | 0.91 | PRMT6 (0.60) | ACE2PRMT6CARM1PRMT8PRMT1 | |
| SCHEMBL20028835 | 0.90 | — | — | |
| SCHEMBL5430626 | 0.90 | PRMT6 (0.58) | ACE2PRMT6CARM1PRMT8KMT2A | |
| SCHEMBL21367124 | 0.89 | ACE2 (0.50) | ACE2PRMT6CARM1PRMT8CYP2C19 | |
| SCHEMBL13008045 | 0.89 | ACE2 (0.50) | ACE2PRMT6CARM1PRMT8CYP2C19 | |
| SCHEMBL16504283 | 0.89 | ACE2 (0.50) | ACE2PRMT6CARM1PRMT8CYP2C19 | |
| SCHEMBL13178507 | 0.87 | PRMT6 (0.56) | ACE2PRMT6CARM1PRMT8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113501796-B | Aminoethylated piperazine and preparation method thereof | 大连理工大学 | 2022-08-26 | — | — | CN | disclosed |
| CN-113477052-B | Aminoethylated piperazine, preparation method thereof, carbon dioxide absorbent and application thereof | 大连理工大学 | 2022-05-24 | — | — | CN | disclosed |
| EP-2688935-B1 | NOVEL GRADATED POLYMERS AND PROCESS FOR THE PREPARATION THEREOF | GT ELEKTROTECHNISCHE PRODUKTE GMBH (DE) | 2016-03-16 | — | — | EP | disclosed |
| EP-2688935-A1 | NOVEL GRADATED POLYMERS AND PROCESS FOR THE PREPARATION THEREOF | GT Elektrotechnische Produkte GmbH (DE) | 2014-01-29 | — | — | EP | disclosed |
| EP-2524934-A2 | Thermoplastic polyurethane urea with biocidal properties and methods for producing same | GT Elektrotechnische Produkte GmbH (DE) | 2012-11-21 | — | — | EP | disclosed |
| WO-2012126638-A1 | NOVEL GRADATED POLYMERS AND PROCESS FOR THE PREPARATION THEREOF | GT ELEKTROTECHNISCHE PRODUKTE GMBH (DE) | 2012-09-27 | — | — | WO | disclosed |
| WO-2008030390-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | MERCK & CO., INC. (US) | 2008-03-13 | — | — | WO | disclosed |
| WO-2008030390-A2 | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION | MERCK & CO., INC. (US) | 2008-03-13 | — | — | WO | disclosed |