SCHEMBL20029720

SCHEMBL20029720

Cc1ccc(-c2ccc(-c3ccc(-c4ccc(F)c(F)c4F)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 11/20 0.51
PTGS1 P23219 4/20 0.50
ACHE P22303 2/20 0.39
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
RPS6KA3 P51812 1/20 0.37
NFE2L2 Q16236 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20029560 1.00 PTGS2 (0.51) PTGS2PTGS1ACHEPDE3BPDE3A
SCHEMBL13301268 0.98 PTGS2 (0.53) PTGS2PTGS1ACHEPDE3BPDE3A
SCHEMBL17570168 0.91 ACHE (0.46) PTGS2PTGS1ACHEPDE3BPDE3A
SCHEMBL172423 0.89 ACHE (0.48) PTGS2PTGS1ACHEPDE3BPDE3A
SCHEMBL22048103 0.84 MEN1 (0.44) PTGS2PTGS1PDE3BPDE3A
SCHEMBL4549715 0.83 PTGS2 (0.40) PTGS2PTGS1ACHEPDE3BPDE3A
SCHEMBL17548830 0.83 PTGS2 (0.40) PTGS2PTGS1ACHEPDE3BPDE3A
SCHEMBL18779837 0.82 RAB9A (0.40) PTGS2PTGS1ACHE
SCHEMBL17359262 0.81 RPS6KA3 (0.46) PTGS2PTGS1ACHEPDE3BPDE3A
SCHEMBL17550730 0.81 MEN1 (0.44) PTGS2PTGS1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10767113-B2 Liquid crystal compound containing 2,3,4-trisubstituted benzene and composition thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2020-09-08 US disclosed
US-20180094191-A1 LIQUID CRYSTAL COMPOUND CONTAINING 2,3,4-TRISUBSTITUTED BENZENE AND COMPOSITION THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO LTD (CN) 2018-04-05 US disclosed