Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030670 | 0.83 | L3MBTL1 (0.32) | MAPTKDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL20030832 | 0.82 | KDM4E (0.40) | HRH4MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL20030678 | 0.81 | KDM4E (0.34) | MAPTKDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL20030472 | 0.81 | L3MBTL1 (0.36) | MAPTKDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL20106638 | 0.80 | KDM4E (0.34) | HRH4PPARGPPARDPPARAKDM4E | |
| SCHEMBL20106636 | 0.80 | KDM4E (0.34) | HRH4PPARGPPARDPPARAKDM4E | |
| SCHEMBL31114844 | 0.80 | KDM4E (0.34) | HRH4PPARGPPARDPPARAKDM4E | |
| SCHEMBL31114904 | 0.80 | KDM4E (0.34) | HRH4PPARGPPARDPPARAKDM4E | |
| SCHEMBL20030761 | 0.79 | KDM4E (0.36) | PPARAMAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL20030619 | 0.79 | KDM4E (0.34) | MAPTKDM4EHPGDHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064080-A1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2018-04-05 | — | — | WO | disclosed |