Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031010 | 0.91 | KMT2A (0.33) | KDM4EALDH1A1AVPR1BCHRM4 | |
| SCHEMBL20030854 | 0.86 | L3MBTL1 (0.34) | L3MBTL1KDM4ESMN1; SMN2TDP1NPC1 | |
| SCHEMBL20030832 | 0.83 | KDM4E (0.40) | L3MBTL1KDM4ESMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL20030668 | 0.83 | HRH4 (0.32) | L3MBTL1KDM4ESMN1; SMN2NPC1PKM | |
| SCHEMBL20030472 | 0.83 | L3MBTL1 (0.36) | L3MBTL1KDM4ESMN1; SMN2TDP1NPC1 | |
| SCHEMBL20030678 | 0.82 | KDM4E (0.34) | L3MBTL1KDM4ESMN1; SMN2TDP1NPC1 | |
| SCHEMBL31114871 | 0.80 | CYP3A4 (0.31) | AVPR1B | |
| SCHEMBL20101195 | 0.80 | CYP3A4 (0.31) | AVPR1B | |
| SCHEMBL20030761 | 0.80 | KDM4E (0.36) | L3MBTL1KDM4ESMN1; SMN2TDP1NPC1 | |
| SCHEMBL20030918 | 0.79 | KDM4E (0.39) | L3MBTL1KDM4ESMN1; SMN2TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064080-A1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2018-04-05 | — | — | WO | disclosed |