⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025541 | 0.75 | — | — | |
| SCHEMBL23015655 | 0.69 | — | — | |
| SCHEMBL6025538 | 0.67 | — | — | |
| SCHEMBL23543063 | 0.67 | — | — | |
| SCHEMBL20031203 | 0.67 | — | — | |
| SCHEMBL21531775 | 0.67 | — | — | |
| SCHEMBL925704 | 0.65 | — | — | |
| SCHEMBL23521071 | 0.65 | — | — | |
| SCHEMBL20097095 | 0.65 | ADH1B (0.32) | — | |
| Hydrochloric Acid SCHEMBL3896192 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2540320-A1 | LEPTOMYCIN DERIVATIVES | SANOFI (FR) | 2013-01-02 | — | — | EP | disclosed |
| EP-2032172-B1 | LEPTOMYCIN DERIVATIVES | SANOFI SA (FR) | 2012-06-06 | — | — | EP | disclosed |
| EP-2448929-A1 | NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-05-09 | — | — | EP | disclosed |
| US-20110002947-A1 | LEPTOMYCIN DERIVATIVES | SANOFI-AVENTIS (FR) | 2011-01-06 | — | — | US | disclosed |
| WO-2011001052-A1 | NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-06 | — | — | WO | disclosed |
| US-7816543-B2 | Leptomycin derivatives | SANOFI-AVENTIS (FR) | 2010-10-19 | — | — | US | disclosed |
| US-20090182038-A1 | Leptomycin Derivatives | SANOFI-AVENTIS (FR) | 2009-07-16 | — | — | US | disclosed |
| EP-2032172-A2 | LEPTOMYCIN DERIVATIVES | Sanofi-Aventis (FR) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007144709-A2 | LEPTOMYCIN DERIVATIVES | SANOFI-AVENTIS (FR) | 2007-12-21 | — | — | WO | disclosed |
| EP-1864682-A1 | Leptomycin derivatives | Sanofi-Aventis (FR) | 2007-12-12 | — | — | EP | disclosed |