Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21490274 | 0.85 | LMNA (0.49) | KDM4EKMT2AALDH1A1RXFP1TTK | |
| SCHEMBL26131533 | 0.81 | AKR1B1 (0.41) | KDM4EKMT2AALDH1A1MEN1HSP90AA1 | |
| SCHEMBL25183446 | 0.79 | PIK3CD (0.41) | KDM4EKMT2AALDH1A1MEN1HSP90AA1 | |
| SCHEMBL13267543 | 0.79 | ALDH1A1 (0.41) | KDM4EKMT2AALDH1A1MEN1HSP90AA1 | |
| SCHEMBL13245188 | 0.79 | SRD5A2 (0.38) | KDM4EKMT2AALDH1A1MEN1HSP90AA1 | |
| SCHEMBL12985724 | 0.78 | TDP1 (0.45) | KDM4EKMT2AALDH1A1MEN1HSP90AA1 | |
| SCHEMBL31132638 | 0.77 | AKR1B1 (0.36) | KDM4EKMT2AALDH1A1MEN1HSP90AA1 | |
| SCHEMBL30943174 | 0.77 | PDE10A (0.51) | AHR | |
| SCHEMBL7921087 | 0.74 | AHR (0.46) | KDM4EKMT2AALDH1A1MEN1RXFP1 | |
| SCHEMBL23320488 | 0.73 | NAMPT (0.55) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831811-A1 | HETEROCYCLIC COMPOUND | Fimecs, Inc. (JP) | 2021-06-09 | — | — | EP | disclosed |
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |