Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.51 |
| ▸ | NAMPT | P43490 | 3/20 | 0.50 |
| ▸ | AHR | P35869 | 7/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943164 | 0.84 | ALDH1A1 (0.53) | PDE10ANAMPTAHR | |
| SCHEMBL16003818 | 0.79 | PDE10A (0.51) | PDE10AAHRDHODHEGFRPARP1 | |
| SCHEMBL26131533 | 0.78 | AKR1B1 (0.41) | AHR | |
| SCHEMBL30943165 | 0.78 | KMO (0.43) | NAMPTAHR | |
| SCHEMBL25183446 | 0.77 | PIK3CD (0.41) | — | |
| SCHEMBL14811257 | 0.77 | AHR (0.51) | PDE10ANAMPTAHREGFRPARP1 | |
| SCHEMBL14811661 | 0.77 | AHR (0.81) | PDE10ANAMPTAHREGFRNR1H2 | |
| SCHEMBL20031271 | 0.77 | KDM4E (0.40) | AHR | |
| SCHEMBL24320353 | 0.76 | AHR (0.47) | PDE10ANAMPTAHREGFR | |
| SCHEMBL15170804 | 0.75 | CYP11B2 (0.53) | PDE10AAHRDHODHEGFRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |