Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436949 | 1.00 | HTR2A (0.53) | HTR2ASLC6A4KCNH2KMT2ALMNA | |
| SCHEMBL47864 | 0.89 | KMT2A (0.60) | HTR2ASLC6A4KCNH2KMT2ALMNA | |
| SCHEMBL10993100 | 0.89 | KMT2A (0.60) | HTR2ASLC6A4KCNH2KMT2ALMNA | |
| SCHEMBL47874 | 0.86 | KMT2A (0.57) | HTR2ASLC6A4KCNH2KMT2ALMNA | |
| SCHEMBL10599282 | 0.85 | HTR2A (0.54) | HTR2ASLC6A4KCNH2KMT2AMAOA | |
| SCHEMBL675954 | 0.85 | HTR2A (0.54) | HTR2ASLC6A4KCNH2KMT2AMAOA | |
| SCHEMBL28478563 | 0.83 | MAOA (0.50) | HTR2ASLC6A4KCNH2KMT2AMAOA | |
| SCHEMBL10984775 | 0.82 | KMT2A (0.55) | HTR2ASLC6A4KMT2ALMNAGFER | |
| SCHEMBL10990207 | 0.82 | KMT2A (0.55) | HTR2ASLC6A4KMT2ALMNAGFER | |
| SCHEMBL257610 | 0.82 | KMT2A (0.55) | HTR2ASLC6A4KMT2ALMNAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409142-B | Preparation method of 4-p-chlorophenoxyl acetophenone compounds | 帕潘纳(北京)科技有限公司 | 2022-04-19 | — | — | CN | disclosed |