Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151166 | 0.77 | SRD5A2 (0.59) | SRD5A2ALDH1A1MAPK1HIF1ATSHR | |
| SCHEMBL6756395 | 0.75 | AHR (0.53) | SRD5A2CNR1 | |
| SCHEMBL7016688 | 0.74 | SRD5A2 (0.64) | SRD5A2ALDH1A1MAPK1HIF1ATSHR | |
| SCHEMBL21550048 | 0.74 | CYP4F2 (0.47) | ALDH1A1MAPK1HIF1ARECQLCYP4F2 | |
| SCHEMBL27259107 | 0.73 | KLKB1 (0.52) | LTB4RLTB4R2ALDH1A1KLKB1TP53 | |
| SCHEMBL11527291 | 0.73 | SMN1; SMN2 (0.49) | LTB4RLTB4R2ALDH1A1TP53TSHR | |
| SCHEMBL27259360 | 0.73 | KLKB1 (0.52) | ALDH1A1KLKB1CASP1KDM4E | |
| SCHEMBL21550015 | 0.72 | ALDH1A1 (0.46) | SRD5A2ALDH1A1MAPK1HIF1ARECQL | |
| SCHEMBL809394 | 0.72 | ALDH1A1 (0.59) | SRD5A2ALDH1A1HIF1ATP53TSHR | |
| SCHEMBL10972202 | 0.71 | MAPK14 (0.51) | HPGDCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |