Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554300 | 0.90 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL6492374 | 0.89 | DHODH (0.55) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL8248300 | 0.87 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL6695209 | 0.86 | PRKAB2 (0.53) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL2558658 | 0.86 | AKR1C3 (0.51) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL15330366 | 0.86 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL6498907 | 0.86 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL23354242 | 0.85 | ANO1 (0.49) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL6489883 | 0.85 | NPC1 (0.51) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL29979920 | 0.85 | ANO1 (0.49) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398120-B2 | Substituted hydantoinamides as ADAMTS7 antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2025-08-26 | — | — | US | disclosed |
| EP-4058448-B1 | HYDANTOIN DERIVATIVES AS ADAMTS7 ANTAGONISTS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | BAYER AG (DE) | 2024-05-29 | — | — | EP | disclosed |
| CN-115793391-A | Photoresist and application thereof | 北京科华微电子材料有限公司 | 2023-03-14 | — | — | CN | disclosed |
| US-20230027346-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-26 | — | — | US | disclosed |
| EP-3822268-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2021-05-19 | — | — | EP | disclosed |
| EP-1845122-B1 | POLYARYLENE, PROCESS FOR PRODUCING THE SAME, SOLID POLYELECTROLYTE, AND PROTON-CONDUCTIVE FILM | JSR CORP (JP) | 2011-11-16 | — | — | EP | disclosed |
| US-7893303-B2 | Polyarylene, process for producing the same, solid polyelectrolyte, and proton-conductive film | JSR CORPORATION (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20080015389-A1 | Polyarylene, Process For Producing The Same, Solid Polyelectrolyte, And Proton-Conductive Film | JSR CORPORATION (JP) | 2008-01-17 | — | — | US | disclosed |
| EP-1845122-A1 | POLYARYLENE, PROCESS FOR PRODUCING THE SAME, SOLID POLYELECTROLYTE, AND PROTON-CONDUCTIVE FILM | JSR Corporation (JP) | 2007-10-17 | — | — | EP | disclosed |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015389-A1 | Polyarylene, Process For Producing The Same, Solid Polyelectrolyte, And Proton-Conductive Film | PARG, PUF60, PARN | ALDH1A1 3441/4885SMN1; SMN2 1535/4885TSHR 3755/4885 |
| US-12398120-B2 | Substituted hydantoinamides as ADAMTS7 antagonists | ADAMTS7, MMP7, ADAM17 | ALDH1A1 3828/4885SMN1; SMN2 3850/4885TSHR 1345/4885 |
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | ALDH1A1 2901/4885SMN1; SMN2 1854/4885TSHR 1272/4885 |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | ALDH1A1 1603/4885SMN1; SMN2 1921/4885TSHR 2021/4885 |
| US-20230027346-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | ADAMTS7, MMP7, ADAM17 | ALDH1A1 3828/4885SMN1; SMN2 3850/4885TSHR 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.