Zinc Ion

Zinc Ion

SCHEMBL2003242

O=C([O-])c1ccccc1OCc1ccccc1.O=C([O-])c1ccccc1OCc1ccccc1.[Zn+2]

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SGMS2 Q8NHU3 4/20 0.62
PARP1 P09874 1/20 0.59
NPC1 O15118 1/20 0.59
HTT P42858 1/20 0.59
GAA P10253 1/20 0.57
LMNA P02545 1/20 0.55
MAPT P10636 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MEN1 O00255 1/20 0.55
ALDH1A1 P00352 1/20 0.55
KMT2A Q03164 1/20 0.55
TRPM8 Q7Z2W7 2/20 0.53
FOLH1 Q04609 1/20 0.53
PTGER1 P34995 1/20 0.52
ALPG P10696 1/20 0.51
PTK2B Q14289 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL29424299 1.00 SGMS2 (0.62) SGMS2PARP1NPC1HTTGAA
SCHEMBL17799484 0.96 SGMS2 (0.62) SGMS2PARP1NPC1HTTGAA
SCHEMBL718082 0.86 PARP1 (0.79) SGMS2PARP1NPC1HTTGAA
SCHEMBL9696207 0.85 SGMS2 (0.66) SGMS2PARP1NPC1HTTGAA
SCHEMBL112903 0.85 SGMS2 (0.66) SGMS2PARP1NPC1HTTGAA
SCHEMBL29433417 0.85 SGMS2 (0.66) SGMS2PARP1NPC1HTTGAA
SCHEMBL4415350 0.84 HTT (0.75) SGMS2PARP1NPC1HTTGAA
SCHEMBL28123581 0.84 SGMS2 (0.60) SGMS2PARP1NPC1HTTGAA
Bicarbonate SCHEMBL236872 0.84 SGMS2 (0.64) SGMS2PARP1NPC1HTTGAA
Bicarbonate SCHEMBL21753662 0.84 SGMS2 (0.64) SGMS2PARP1NPC1HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172178-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2018-09-12 EP disclosed
EP-3172178-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2017-05-31 EP disclosed
WO-2016012305-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2016-01-28 WO disclosed
CN-101255232-B Process for preparing organosilicon compounds having organyloxy groups Wacker-Chemie GmbH (DE) Prinzregentenstrasse 22, Postfach 8000, Munich, F.R.G. (DE) 2011-11-30 CN disclosed
US-7960577-B2 Process for preparing organosilicon compounds having organyloxy groups WACKER CHEMIE AG (DE) 2011-06-14 US disclosed
EP-1964872-B1 Process for preparing organosilicon compounds having organyloxy groups WACKER CHEMIE AG (DE) 2009-10-21 EP disclosed
EP-1964872-A1 Process for preparing organosilicon compounds having organyloxy groups Wacker Chemie AG (DE) 2008-09-03 EP disclosed
CN-101255232-A Process for preparing organosilicon compounds having organyloxy groups WACKER CHEMIE AG (DE) 2008-09-03 CN disclosed