Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.79 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875473 | 0.87 | PTGER1 (0.62) | PARP1HTTSGMS2NPC1PARP10 | |
| SCHEMBL7689226 | 0.87 | PARP1 (0.61) | PARP1HTTSGMS2LMNAMEN1 | |
| Zinc Ion SCHEMBL29424299 | 0.86 | SGMS2 (0.62) | PARP1HTTSGMS2LMNAMEN1 | |
| SCHEMBL17799484 | 0.86 | SGMS2 (0.62) | PARP1HTTSGMS2LMNAMEN1 | |
| Zinc Ion SCHEMBL2003242 | 0.86 | SGMS2 (0.62) | PARP1HTTSGMS2LMNAMEN1 | |
| SCHEMBL875475 | 0.85 | PARP1 (0.60) | PARP1HTTSGMS2LMNAMEN1 | |
| SCHEMBL12505427 | 0.85 | PARP1 (0.64) | PARP1HTTLMNAMEN1KMT2A | |
| SCHEMBL29433417 | 0.85 | SGMS2 (0.66) | PARP1HTTSGMS2LMNAKMT2A | |
| SCHEMBL112903 | 0.85 | SGMS2 (0.66) | PARP1HTTSGMS2LMNAKMT2A | |
| SCHEMBL9696207 | 0.85 | SGMS2 (0.66) | PARP1HTTSGMS2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109876157-A | Ion specificity filter membrane/mesoporous silicon composite material, nano-sensor and products thereof and application | 浙江大学 | 2019-06-14 | — | — | CN | claimed |
| EP-2616439-B1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | COUNCIL SCIENT IND RES (IN) | 2015-12-16 | — | — | EP | claimed |
| EP-2010508-A1 | THIAZOL-GUANIDINE DERIVATIVES USEFUL AS A (BETA)- RELATED PATHOLOGIES | AstraZeneca AB (SE) | 2009-01-07 | — | — | EP | claimed |
| WO-2007120096-A1 | THIAZOL-GUANIDINE DERIVATIVES USEFUL AS A (BETA)- RELATED PATHOLOGIES | ASTRAZENECA AB (SE) | 2007-10-25 | — | — | WO | claimed |
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| EP-0666840-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-16 | — | — | EP | claimed |
| WO-1995006630-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-09 | — | — | WO | claimed |
| JP-57144246-A | — | — | None | — | — | JP | disclosed |
| CN-118290332-A | Preparation method of polyphenol compound | 江西理工大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-113677334-B | Transient receptor potential MELASTATIN 8 (TRPM 8) antagonists and related methods | 马歇尔大学科研协会 | 2024-04-09 | — | — | CN | disclosed |
| CN-115028679-B | PROTAC compound with Cyclophilin A degradation activity and preparation method and application thereof | 深圳湾实验室 | 2022-11-15 | — | — | CN | disclosed |
| US-20220313629-A1 | TRANSIENT POTENTIAL MELASTATIN 8 (TRPM8) ANTAGONISTS AND RELATED METHODS | MARSHALL UNIVERSITY RESEARCH CORPORATION | 2022-10-06 | — | — | US | disclosed |
| EP-0323887-A2 | Heat-sensitive diazo recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-12 | — | — | EP | disclosed |
| EP-0136745-B1 | BENZOYL UREA DERIVATIVES HAVING ANTI-TUMOR ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-06-07 | — | — | EP | disclosed |
| EP-0136745-A2 | Benzoyl urea derivatives having anti-tumor activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1985-04-10 | — | — | EP | disclosed |
| EP-0015505-B1 | 3-AMINO-1,2-PROPANE DIOLS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USE THEREOF | CIBA-GEIGY AG (CH) | 1984-08-08 | — | — | EP | disclosed |
| JP-S57144246-A | O-BENZYLOXYBENZOIC ACID AMIDE DERIVATIVE AND HERBICIDE CONTAINING THE SAME | HODOGAYA CHEM CO LTD | 1982-09-06 | — | — | JP | disclosed |
| EP-0015505-A1 | 3-Amino-1,2-propane diols, process for their preparation, pharmaceutical compositions containing them and use thereof | CIBA-GEIGY AG (CH) | 1980-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220313629-A1 | TRANSIENT POTENTIAL MELASTATIN 8 (TRPM8) ANTAGONISTS AND RELATED METHODS | TRPM8, TRPV1, TRPM7 | PARP1 3144/4885HTT 4031/4885SGMS2 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.