Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 3/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 9/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 9/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 9/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22620788 | 0.88 | GNAI3 (0.40) | GNAI3GNAI1TGM2TPSAB1TPSD1 | |
| SCHEMBL20019652 | 0.84 | GNAI3 (0.37) | GNAI3GNAI1TGM2TPSAB1TPSD1 | |
| SCHEMBL14980274 | 0.82 | GNAI3 (0.44) | GNAI3GNAI1TGM2TPSAB1TPSD1 | |
| SCHEMBL15443875 | 0.82 | GNAI3 (0.39) | GNAI3GNAI1TGM2TPSAB1TPSD1 | |
| SCHEMBL23713937 | 0.82 | GNAI3 (0.41) | GNAI3GNAI1TGM2TPSAB1TPSD1 | |
| SCHEMBL27336659 | 0.80 | GNAI3 (0.41) | GNAI3GNAI1TGM2TPSAB1TPSD1 | |
| SCHEMBL12284392 | 0.79 | PRMT1 (0.44) | GNAI3GNAI1TGM2TPSAB1TPSD1 | |
| SCHEMBL15355591 | 0.79 | GNAI3 (0.41) | GNAI3GNAI1TGM2TPSAB1TPSD1 | |
| SCHEMBL12283544 | 0.79 | ALDH1A1 (0.51) | GNAI3GNAI1TPSAB1TPSD1TPSG1 | |
| SCHEMBL19464837 | 0.79 | HRH3 (0.42) | GNAI3GNAI1TGM2TPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788487-B1 | OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNA | SAREPTA THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |