Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21231402 | 0.90 | KMO (0.49) | KMO | |
| SCHEMBL16614133 | 0.90 | KMO (0.49) | KMO | |
| SCHEMBL18084711 | 0.88 | KMO (0.36) | KMO | |
| SCHEMBL21231366 | 0.88 | KMO (0.36) | KMO | |
| SCHEMBL20032577 | 0.85 | KMO (0.39) | KMO | |
| SCHEMBL21218966 | 0.75 | KMO (0.51) | KMO | |
| SCHEMBL16600309 | 0.75 | KMO (0.51) | KMO | |
| SCHEMBL16600346 | 0.75 | KMO (0.51) | KMO | |
| SCHEMBL21231297 | 0.75 | KMO (0.51) | KMO | |
| SCHEMBL20032575 | 0.74 | NPC1 (0.45) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938252-B2 | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof | CHDI FOUNDATION, INC. (US) | 2018-04-10 | — | — | US | disclosed |