Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20032688 | 0.82 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9ASLC6A3 | |
| SCHEMBL1186911 | 0.82 | MEN1 (0.52) | MEN1KMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL225085 | 0.80 | KMT2A (0.65) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10827630 | 0.80 | MEN1 (0.45) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9860310 | 0.80 | MEN1 (0.53) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL18101784 | 0.80 | KMT2A (0.46) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9875684 | 0.79 | HSD11B1 (0.39) | MEN1KMT2ANPC1RAB9ASLC6A3 | |
| SCHEMBL2281345 | 0.79 | SMN1; SMN2 (0.60) | MEN1KMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL26452181 | 0.79 | PARP10 (0.58) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| Benzoin SCHEMBL54015 | 0.79 | LMNA (0.55) | MEN1KMT2ACES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104414-A1 | ENANTIOSELECTIVE SYNTHESIS | SCHERING CORPORATION (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009493-A1 | ENANTIOSELECTIVE SYNTHESIS | SCHERING CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |