SCHEMBL20033062

SCHEMBL20033062

Br/C(=N/c1ccccc1)c1cccc(Br)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
C1S P09871 1/20 0.46
PARP1 P09874 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
HPGD P15428 2/20 0.45
GAA P10253 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 1/20 0.42
ALOX12 P18054 1/20 0.42
MAPT P10636 1/20 0.41
ALDH1A1 P00352 2/20 0.41
TP53 P04637 1/20 0.41
CTSL P07711 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12076821 0.81 MEN1 (0.66) C1SPARP1SMN1; SMN2HPGDGAA
SCHEMBL12092316 0.81 MEN1 (0.66) C1SPARP1SMN1; SMN2HPGDGAA
SCHEMBL12076824 0.81 MEN1 (0.66) C1SPARP1SMN1; SMN2HPGDGAA
SCHEMBL4668221 0.77 ESR1 (0.50) C1SSMN1; SMN2HPGDGAANFKB1
Ammonia Solution, Strong SCHEMBL4910431 0.76 ESR1 (0.48) C1SSMN1; SMN2HPGDGAANFKB1
SCHEMBL20033061 0.75 GRIN2D (0.43) SMN1; SMN2HPGDMEN1KMT2ALMNA
SCHEMBL20894576 0.73 PARP1 (0.59) C1SPARP1SMN1; SMN2HPGDGAA
SCHEMBL1744811 0.69 C1S (0.50) C1SPARP1SMN1; SMN2HPGDGAA
SCHEMBL40538 0.69 ATM (0.71) PARP1SMN1; SMN2HPGDGAANFKB1
SCHEMBL4229652 0.69 CES2 (0.61) C1SPARP1SMN1; SMN2HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9938287-B1 Blue fluorescence dopant compound and organic electroluminescent device using the same NANJING TOPTO MATERIALS CO.,LTD. (CN) 2018-04-10 US disclosed