Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.36 |
| ▸ | KIF11 | P52732 | 6/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20033410 | 0.89 | CLK4 (0.36) | CYP11B2CYP11B1KIF11CLK4DYRK1A | |
| SCHEMBL20033411 | 0.88 | PDE2A (0.34) | CLK4DYRK1APDE2AALOX5APFEN1 | |
| SCHEMBL14681256 | 0.86 | CYP11B2 (0.39) | CYP11B2CYP11B1KIF11 | |
| SCHEMBL20033405 | 0.86 | CYP11B2 (0.40) | CYP11B2CYP11B1 | |
| SCHEMBL18486761 | 0.79 | FFAR1 (0.32) | CLK4DYRK1A | |
| SCHEMBL15773574 | 0.77 | CYP11B2 (0.45) | CYP11B2CYP11B1KIF11HDAC6ALOX5AP | |
| SCHEMBL15773587 | 0.75 | CYP11B2 (0.38) | CYP11B2CYP11B1KIF11ALOX5APFEN1 | |
| SCHEMBL20033412 | 0.75 | FFAR1 (0.40) | CYP11B2CYP11B1 | |
| SCHEMBL20113143 | 0.75 | CCR6 (0.32) | — | |
| SCHEMBL15773593 | 0.75 | CYP11B1 (0.35) | CYP11B2CYP11B1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938464-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |