Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18486761 | 0.91 | FFAR1 (0.32) | CLK4DYRK1A | |
| SCHEMBL20033406 | 0.88 | CYP11B2 (0.36) | PDE2ACLK4DYRK1AALOX5APFEN1 | |
| SCHEMBL20033409 | 0.85 | EGLN2 (0.34) | CLK4 | |
| SCHEMBL15605577 | 0.84 | HDAC4 (0.30) | — | |
| SCHEMBL22035305 | 0.82 | — | — | |
| SCHEMBL18499521 | 0.80 | KIF11 (0.37) | PDE2A | |
| SCHEMBL20033530 | 0.79 | PDE2A (0.37) | PDE2A | |
| SCHEMBL16844165 | 0.77 | TRPA1 (0.33) | — | |
| SCHEMBL16193041 | 0.76 | SMN1; SMN2 (0.37) | PDE2A | |
| SCHEMBL20033405 | 0.76 | CYP11B2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925834-B1 | LENS ELEMENT | MERCK PATENT GMBH (DE) | 2018-07-04 | — | — | EP | disclosed |
| US-9938464-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |