SCHEMBL18486761

SCHEMBL18486761

Fc1cc(OC(F)(F)c2c(F)cc(-c3ncccn3)cc2F)cc(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 1/20 0.32
▸ CLK4 Q9HAZ1 2/20 0.32
▸ DYRK1A Q13627 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20033411 0.91 PDE2A (0.34) CLK4DYRK1A
SCHEMBL22035305 0.90 — —
SCHEMBL20033409 0.85 EGLN2 (0.34) CLK4
SCHEMBL10001791 0.84 HDAC4 (0.30) —
SCHEMBL20033410 0.84 CLK4 (0.36) FFAR1CLK4DYRK1A
SCHEMBL18486762 0.83 FFAR1 (0.42) FFAR1
SCHEMBL20033406 0.79 CYP11B2 (0.36) CLK4DYRK1A
SCHEMBL12760433 0.79 NPC1 (0.33) —
SCHEMBL18455346 0.78 AKR1C2 (0.35) —
SCHEMBL27972145 0.78 CYP2A6 (0.38) FFAR1CLK4DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 — — US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 — — US disclosed
US-11760931-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-09-19 — — US disclosed
US-11718791-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2023-08-08 — — US disclosed
US-20230056437-A1 AZO DYE MERCK PATENT GMBH (DE) 2023-02-23 — — US disclosed
US-20230053362-A1 DICHROIC DYE COMPOSITION MERCK PATENT GMBH (DE) 2023-02-23 — — US disclosed
US-20230029961-A1 LIQUID CRYSTAL MEDIA COMPRISING POLYMERISABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-02-02 — — US disclosed
US-11168257-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2021-11-09 — — US disclosed
US-20210284912-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2021-09-16 — — US disclosed
US-20210238481-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (JP) 2021-08-05 — — US disclosed
US-20210024826-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2021-01-28 — — US disclosed
US-10626330-B2 Method for manufacturing a liquid crystal display device and liquid crystal mixture MERCK PATENT GMBH (DE) 2020-04-21 — — US disclosed
US-20190241809-A1 COMPOUNDS FOR THE HOMEOTROPIC ALIGNMENT OF LIQUID-CRYSTALLINE MEDIA MERCK PATENT GMBH (DE) 2019-08-08 — — US disclosed
US-20190153320-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-05-23 — — US disclosed
US-20190127642-A1 COMPOSITION FOR NANOENCAPSULATION AND NANOCAPSULES COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-05-02 — — US disclosed
US-20190002763-A1 METHOD FOR MANUFACTURING A LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL MIXTURE MERCK PATENT GMBH (DE) 2019-01-03 — — US disclosed
US-20180223187-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2018-08-09 — — US disclosed
US-9944416-B2 Filling device and use thereof for dispensing a fluid MERCK PATENT GMBH (DE) 2018-04-17 — — US disclosed
US-9611428-B2 Liquid-crystalline medium and electro-optical liquid-crystal display MERCK PATENT GMBH (DE) 2017-04-04 — — US disclosed
US-20170037315-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718791-B2 Polymerisable compounds and the use thereof in liquid-crystal displays VCL, ILK, LCP1 FFAR1 4194/4885CLK4 352/4885DYRK1A 1242/4885
US-20210238481-A1 LIQUID CRYSTALLINE MEDIUM NEFM, CCNI, MYT1 FFAR1 3117/4885CLK4 3207/4885DYRK1A 4357/4885
US-20190002763-A1 METHOD FOR MANUFACTURING A LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL MIXTURE MAP1LC3C, MAP1LC3A, MAP1LC3B FFAR1 2593/4885CLK4 89/4885DYRK1A 129/4885
US-10626330-B2 Method for manufacturing a liquid crystal display device and liquid crystal mixture MAP1LC3C, MAP1LC3A, MAP1LC3B FFAR1 2593/4885CLK4 89/4885DYRK1A 129/4885
US-20210284912-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY CXCR1, PYM1, F11 FFAR1 2001/4885CLK4 976/4885DYRK1A 3317/4885
US-20190241809-A1 COMPOUNDS FOR THE HOMEOTROPIC ALIGNMENT OF LIQUID-CRYSTALLINE MEDIA NEFM, MDN1, VCL FFAR1 2291/4885CLK4 1573/4885DYRK1A 1953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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