Zinc Ion

Zinc Ion

SCHEMBL2003364

CCOc1ccccc1C(=O)[O-].CCOc1ccccc1C(=O)[O-].[Zn+2]

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.60
L3MBTL1 Q9Y468 4/20 0.53
GLA P06280 1/20 0.53
MAPT P10636 5/20 0.53
MAPK1 P28482 2/20 0.53
GAA P10253 1/20 0.53
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HSD17B10 Q99714 3/20 0.50
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.50
HPGD P15428 2/20 0.50
HTT P42858 1/20 0.50
KCNK3 O14649 1/20 0.49
KCNK9 Q9NPC2 1/20 0.49
RAB9A P51151 1/20 0.49
NR1I2 O75469 1/20 0.49
CHRM2 P08172 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL29424296 1.00 HCRTR1 (0.60) HCRTR1L3MBTL1GLAMAPTMAPK1
SCHEMBL5709037 0.96 HCRTR1 (0.60) HCRTR1L3MBTL1GLAMAPTMAPK1
SCHEMBL31721706 0.96 HCRTR1 (0.60) HCRTR1L3MBTL1GLAMAPTMAPK1
SCHEMBL11412992 0.96 HCRTR1 (0.60) HCRTR1L3MBTL1GLAMAPTMAPK1
Zinc Ion SCHEMBL10758637 0.85 PARP1 (0.47) HCRTR1MAPTMEN1KMT2AKDM4E
Zinc Ion SCHEMBL1999542 0.84 LMNA (0.65) L3MBTL1MAPTMAPK1MEN1KMT2A
Ethenzamide SCHEMBL27612766 0.83 MAPT (0.68) HCRTR1L3MBTL1GLAMAPTMAPK1
Ethenzamide SCHEMBL25624 0.83 MAPT (0.68) HCRTR1L3MBTL1GLAMAPTMAPK1
SCHEMBL16180423 0.82 KMT2A (0.56) HCRTR1L3MBTL1MAPTMAPK1GAA
SCHEMBL6969031 0.82 HCRTR1 (0.66) HCRTR1L3MBTL1GLAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172178-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2018-09-12 EP disclosed
US-7960577-B2 Process for preparing organosilicon compounds having organyloxy groups WACKER CHEMIE AG (DE) 2011-06-14 US disclosed
EP-1964872-B1 Process for preparing organosilicon compounds having organyloxy groups WACKER CHEMIE AG (DE) 2009-10-21 EP disclosed
EP-1964872-A1 Process for preparing organosilicon compounds having organyloxy groups Wacker Chemie AG (DE) 2008-09-03 EP disclosed