Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19847478 | 0.95 | TSHR (0.39) | EPHX1TSHRNAAAKDM4EPOLB | |
| SCHEMBL8738483 | 0.91 | THRB (0.41) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL21671197 | 0.91 | THRB (0.41) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL18123481 | 0.88 | THRB (0.45) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL14048840 | 0.88 | THRB (0.39) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL18123480 | 0.88 | TSHR (0.44) | THRBEPHX1TSHRNAAAPOLB | |
| SCHEMBL8738995 | 0.88 | TSHR (0.41) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL8738965 | 0.86 | TSHR (0.42) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL18123478 | 0.86 | TSHR (0.45) | THRBEPHX1TSHRNAAAPOLB | |
| SCHEMBL24089237 | 0.86 | THRB (0.43) | THRBEPHX1TSHRALDH1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9937105-B2 | High strength dental material | DENTSPLY SIRONA INC. (US) | 2018-04-10 | — | — | US | disclosed |