Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21671197 | 0.96 | THRB (0.41) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL8738483 | 0.96 | THRB (0.41) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL8738995 | 0.92 | TSHR (0.41) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL18123481 | 0.92 | THRB (0.45) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL18123480 | 0.92 | TSHR (0.44) | THRBEPHX1TSHRNAAAACHE | |
| SCHEMBL18123478 | 0.91 | TSHR (0.45) | THRBEPHX1TSHRNAAAACHE | |
| SCHEMBL8738965 | 0.91 | TSHR (0.42) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL8738485 | 0.89 | TSHR (0.36) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL20034149 | 0.88 | THRB (0.35) | THRBEPHX1TSHRALDH1A1NPC1 | |
| SCHEMBL21667370 | 0.86 | TSHR (0.41) | THRBEPHX1TSHRNAAAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975708-A2 | Lithographic printing plate precursor | FUJIFILM Corporation (JP) | 2008-10-01 | — | — | EP | disclosed |