Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8738995 | 0.99 | TSHR (0.41) | TSHRTHRBEPHX1ALDH1A1POLB | |
| SCHEMBL18123478 | 0.97 | TSHR (0.45) | TSHRTHRBEPHX1POLBAPEX1 | |
| SCHEMBL18123480 | 0.96 | TSHR (0.44) | TSHRTHRBEPHX1POLBAPEX1 | |
| SCHEMBL16657531 | 0.95 | TSHR (0.38) | TSHRTHRBEPHX1 | |
| SCHEMBL8738483 | 0.94 | THRB (0.41) | TSHRTHRBEPHX1ALDH1A1NAAA | |
| SCHEMBL21671197 | 0.94 | THRB (0.41) | TSHRTHRBEPHX1ALDH1A1NAAA | |
| SCHEMBL21667370 | 0.92 | TSHR (0.41) | TSHRTHRBEPHX1POLBAPEX1 | |
| SCHEMBL18123481 | 0.91 | THRB (0.45) | TSHRTHRBEPHX1ALDH1A1POLB | |
| SCHEMBL14048840 | 0.91 | THRB (0.39) | TSHRTHRBEPHX1ALDH1A1NAAA | |
| SCHEMBL21671200 | 0.90 | TSHR (0.40) | TSHRTHRBEPHX1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220304901-A1 | PHOTOPOLYMERIZABLE RESIN COMPOSITIONS FOR DURABLE DENTAL PROSTHETIC AND RESTORATIVE ARTICLES | DENTSPLY SIRONA INC. (US) | 2022-09-29 | — | — | US | disclosed |
| US-9937105-B2 | High strength dental material | DENTSPLY SIRONA INC. (US) | 2018-04-10 | — | — | US | disclosed |
| US-9937105-B2 | High strength dental material | DENTSPLY SIRONA INC. (US) | 2018-04-10 | — | — | US | disclosed |
| US-20150196462-A1 | HIGH STRENGTH DENTAL MATERIAL | DENTSPLY SIRONA INC. | 2015-07-16 | — | — | US | disclosed |
| US-20150196462-A1 | HIGH STRENGTH DENTAL MATERIAL | DENTSPLY SIRONA INC. | 2015-07-16 | — | — | US | disclosed |
| US-9011150-B2 | High strength dental material | DENTSPLY INTERNATIONAL INC. (US) | 2015-04-21 | — | — | US | disclosed |
| US-9011150-B2 | High strength dental material | DENTSPLY INTERNATIONAL INC. (US) | 2015-04-21 | — | — | US | disclosed |
| WO-2012071329-A2 | HIGH STRENGTH DENTAL MATERIAL | DENTSPLY INTERNATIONAL INC (US) | 2012-05-31 | — | — | WO | disclosed |
| US-20120129973-A1 | HIGH STRENGTH DENTAL MATERIAL | DENTSPLY INTERNATIONAL INC (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120129973-A1 | HIGH STRENGTH DENTAL MATERIAL | DENTSPLY INTERNATIONAL INC (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150196462-A1 | HIGH STRENGTH DENTAL MATERIAL | SMCHD1, CAD, DSG1 | TSHR 4776/4885THRB 4626/4885EPHX1 1587/4885 |
| US-20220304901-A1 | PHOTOPOLYMERIZABLE RESIN COMPOSITIONS FOR DURABLE DENTAL PROSTHETIC AND RESTORATIVE ARTICLES | KDM3A, PSMA3, NOX3 | TSHR 4305/4885THRB 4099/4885EPHX1 1655/4885 |
| US-20120129973-A1 | HIGH STRENGTH DENTAL MATERIAL | SMCHD1, CAD, DSG1 | TSHR 4776/4885THRB 4626/4885EPHX1 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.