Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25839430 | 0.87 | L3MBTL1 (0.43) | LMNAL3MBTL1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL19012592 | 0.86 | GPR119 (0.37) | LMNAMAPTSMN1; SMN2TSHRKDM4E | |
| SCHEMBL18436356 | 0.85 | USP2 (0.41) | MAPTMAPK1SMN1; SMN2ALOX12ALDH1A1 | |
| SCHEMBL19012741 | 0.85 | ACACB (0.41) | LMNAL3MBTL1MAPTMAPK1HTT | |
| SCHEMBL19012736 | 0.82 | MAPT (0.39) | LMNAL3MBTL1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL19012720 | 0.82 | L3MBTL1 (0.39) | LMNAL3MBTL1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL19012400 | 0.75 | SMO (0.44) | LMNAMAPTSMN1; SMN2HTTKDM4E | |
| SCHEMBL19012461 | 0.75 | ACACB (0.41) | LMNAL3MBTL1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL19012457 | 0.73 | GAA (0.44) | LMNAMAPTKDM4EGAAALOX15 | |
| SCHEMBL19012646 | 0.73 | ACACB (0.45) | LMNAMAPTMAPK1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938292-B2 | Quinoline derivatives as SMO inhibitors | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-04-10 | — | — | US | disclosed |