Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29423655 | 0.89 | ALDH1A1 (0.63) | — | |
| SCHEMBL29360795 | 0.85 | KAT8 (0.58) | GLSKAT8 | |
| SCHEMBL29390929 | 0.81 | ALDH1A1 (0.60) | — | |
| SCHEMBL29359926 | 0.79 | ALDH1A1 (0.65) | — | |
| SCHEMBL14987008 | 0.79 | GLS (1.00) | GLS | |
| SCHEMBL14987158 | 0.77 | GLS (1.00) | GLS | |
| SCHEMBL14986989 | 0.77 | GLS (1.00) | GLSKAT8 | |
| SCHEMBL29423653 | 0.77 | RAB9A (0.58) | GLSKAT8 | |
| SCHEMBL19920277 | 0.76 | GLS (0.78) | GLSKAT8 | |
| SCHEMBL29362473 | 0.76 | ALDH1A1 (0.65) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938267-B2 | Heterocyclic inhibitors of glutaminase | CALITHERA BIOSCIENCES, INC. (US) | 2018-04-10 | — | — | US | disclosed |