SCHEMBL2003707

SCHEMBL2003707

NC1C=COc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ATM Q13315 1/20 0.34
CYP2C9 P11712 1/20 0.32
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2009020 0.74 MAOA (0.35) MAOAMAOBATM
SCHEMBL8948699 0.74 MAOA (0.45) MAOAMAOBATMCYP2C9
SCHEMBL7039784 0.74 MAOA (0.35) MAOAMAOBATM
SCHEMBL12808890 0.74 MAOA (0.35) MAOAMAOBATM
SCHEMBL276293 0.74 MAOA (0.35) MAOAMAOBATMCYP2C9
SCHEMBL294504 0.74 MAOA (0.35) MAOAMAOBATM
SCHEMBL294505 0.74 MAOA (0.35) MAOAMAOBATM
SCHEMBL9772861 0.74 HTR2A (0.36) MAOAMAOBATMHTR2A
Hydrochloric Acid SCHEMBL7284607 0.72 MAOA (0.43) MAOAMAOBATMCYP2C9
SCHEMBL4822373 0.70 HTR2A (0.42) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708875-A Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2025-03-28 CN claimed
CN-119708875-B Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2026-03-17 CN disclosed
CN-119708875-B Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2026-03-17 CN disclosed
CN-119708875-A Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2025-03-28 CN disclosed
CN-119708875-A Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2025-03-28 CN disclosed
CN-119708875-A Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2025-03-28 CN disclosed
US-7964623-B2 Tricyclic benzopyrane compound NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2011-06-21 US disclosed
EP-1732929-B1 TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS NISSAN CHEMICAL IND LTD (JP) 2010-10-20 EP disclosed
US-20100069374-A1 Tricyclic benzopyrane compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-03-18 US disclosed
US-7652008-B2 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-26 US disclosed
US-20080004262-A1 Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2008-01-03 US disclosed
EP-1732929-A1 TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS Nissan Chemical Industries, Ltd. (JP) 2006-12-20 EP disclosed
CN-1250536-C 4-aminobenzopyran derivatives NISSAN CHEMICAL IND LTD (JP) 2006-04-12 CN disclosed
WO-2005090357-A1 TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-29 WO disclosed
US-6809114-B2 ANTIARRHYTHMIC AGENTS; SUCH AS 6-ACETYLAMINO-3,4-DIHYDRO-2,2-DIMETHYL-7-NITRO-4-N-PENTYLAMINO-2H-1 -BENZOPYRAN-3-OL NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-10-26 US disclosed
CN-1529702-A 4-aminobenzopyran derivatives �ղ���ѧ��ҵ��ʽ���� 2004-09-15 CN disclosed
US-20040068002-A1 4-aminobenzopyran derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-08 US disclosed
EP-0412760-B1 Benzopyran derivatives BEECHAM GROUP PLC (GB) 1994-11-23 EP disclosed
EP-0412760-A2 Benzopyran derivatives Beecham Group p.l.c. (GB) 1991-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069374-A1 Tricyclic benzopyrane compound CBR1, CBR3, CYP2C9 MAOA 2017/4885MAOB 1658/4885ATM 3916/4885
US-20040068002-A1 4-aminobenzopyran derivatives CYP2D6, KCNH1, CYP2B6 MAOA 1509/4885MAOB 918/4885ATM 4018/4885
US-20080004262-A1 Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents CBR1, CBR3, SCN8A MAOA 2329/4885MAOB 1824/4885ATM 4018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.