SCHEMBL7039784

SCHEMBL7039784

BrC1C=COc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9245713 0.76 CYP2C9 (0.39) MAOAMAOBATM
SCHEMBL21879795 0.76 ATM (0.38) MAOAMAOBATM
SCHEMBL12808890 0.74 MAOA (0.35) MAOAMAOBATM
SCHEMBL276293 0.74 MAOA (0.35) MAOAMAOBATM
SCHEMBL8948699 0.74 MAOA (0.45) MAOAMAOBATM
SCHEMBL2003707 0.74 MAOA (0.35) MAOAMAOBATM
SCHEMBL294505 0.74 MAOA (0.35) MAOAMAOBATM
SCHEMBL294504 0.74 MAOA (0.35) MAOAMAOBATM
SCHEMBL2009020 0.74 MAOA (0.35) MAOAMAOBATM
Hydrochloric Acid SCHEMBL7284607 0.72 MAOA (0.43) MAOAMAOBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030065189-A1 Processes for producing 4-substituted benzopyran derivatives CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-04-03 US claimed
EP-1120412-A1 PROCESSES FOR THE PREPARATION OF 4-SUBSTITUTED BENZOPYRAN DERIVATIVES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2001-08-01 EP claimed
US-6608217-B2 Process for producing 4-substituted benzopyran derivatives CENTRAL GLASS COMPANY, LIMITED (JP) 2003-08-19 US disclosed
US-20030109574-A1 Process for producing 4-substituted benzopyran derivatives CENTRAL GLASS COMPANY, LIMITED (JP) 2003-06-12 US disclosed
US-20030065189-A1 Processes for producing 4-substituted benzopyran derivatives CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-04-03 US disclosed
EP-1298129-A2 Process for producing 4-sustituted benzopyran derivatives Central Glass Company, Limited (JP) 2003-04-02 EP disclosed
US-6455708-B1 SUCH AS 2,2-BIS(FLUOROMETHYL)-N-(2-CYANOETHYL)-6-TRIFLUOROMETHYL-2H-1-BENZOPYRAN-4 -CARBOXAMIDE; USEFUL AS MEDICINES, AGRICHEMICALS AND COSMETICS, AND CHEMICAL INTERMEDIATES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2002-09-24 US disclosed
EP-1120412-A1 PROCESSES FOR THE PREPARATION OF 4-SUBSTITUTED BENZOPYRAN DERIVATIVES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065189-A1 Processes for producing 4-substituted benzopyran derivatives CYP3A4, PARP14, BTD MAOA 411/4885MAOB 427/4885ATM 4472/4885
US-20030109574-A1 Process for producing 4-substituted benzopyran derivatives ACSL4, HAO2, ACSL6 MAOA 1590/4885MAOB 1394/4885ATM 4428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.