SCHEMBL2003709

SCHEMBL2003709

NC1=CCOc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.42
TSHR P16473 1/20 0.42
LMNA P02545 3/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.37
ITGB2 P05107 1/20 0.37
ICAM1 P05362 1/20 0.37
ITGAL P20701 1/20 0.37
MAOB P27338 6/20 0.36
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP19A1 P11511 1/20 0.34
CRHBP P24387 2/20 0.33
CRHR2 Q13324 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7039789 0.78 PKM (0.42) PKMTSHRLMNAALDH1A1KDM4E
SCHEMBL11845341 0.74 PKM (0.42) PKMTSHRLMNAALDH1A1KDM4E
SCHEMBL294469 0.74 TSHR (0.42) PKMTSHRLMNAALDH1A1KDM4E
SCHEMBL294470 0.74 PKM (0.42) PKMTSHRLMNAKMT2AABCG2
SCHEMBL30218838 0.74 PKM (0.42) PKMTSHRLMNAALDH1A1KDM4E
SCHEMBL276292 0.74 PKM (0.47) PKMTSHRLMNAKMT2AABCG2
SCHEMBL29474944 0.74 PKM (0.42) PKMTSHRLMNAKMT2AABCG2
SCHEMBL5541737 0.74 PKM (0.42) PKMTSHRLMNAALDH1A1KDM4E
SCHEMBL2009018 0.74 PKM (0.42) PKMTSHRLMNAALDH1A1KDM4E
SCHEMBL9724429 0.74 PKM (0.38) PKMTSHRLMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708875-A Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2025-03-28 CN claimed
CN-119708875-B Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2026-03-17 CN disclosed
CN-119708875-B Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2026-03-17 CN disclosed
CN-119708875-A Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2025-03-28 CN disclosed
CN-119708875-A Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2025-03-28 CN disclosed
CN-119708875-A Mitochondrial DNA targeted 4-aminobenzopyran photosensitive dye and preparation method and application thereof 河南师范大学 2025-03-28 CN disclosed
CN-107266345-B (hetero) arylcyclopropylamine compounds as LSD1 inhibitors 奥瑞泽恩基因组学股份有限公司 2021-08-17 CN disclosed
EP-3736265-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS Oryzon Genomics, S.A. (ES) 2020-11-11 EP disclosed
EP-2768805-B1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS SA (ES) 2020-03-25 EP disclosed
US-10329256-B2 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors ORYZON GENOMICS, S.A. (ES) 2019-06-25 US disclosed
CN-1250536-C 4-aminobenzopyran derivatives NISSAN CHEMICAL IND LTD (JP) 2006-04-12 CN disclosed
WO-2005090357-A1 TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-29 WO disclosed
US-6809114-B2 ANTIARRHYTHMIC AGENTS; SUCH AS 6-ACETYLAMINO-3,4-DIHYDRO-2,2-DIMETHYL-7-NITRO-4-N-PENTYLAMINO-2H-1 -BENZOPYRAN-3-OL NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-10-26 US disclosed
CN-1529702-A 4-aminobenzopyran derivatives �ղ���ѧ��ҵ��ʽ���� 2004-09-15 CN disclosed
CN-1529702-A 4-aminobenzopyran derivatives �ղ���ѧ��ҵ��ʽ���� 2004-09-15 CN disclosed
CN-1520406-A Antiarrhythmic substituted benzopyran derivatives �ղ���ѧ��ҵ��ʽ���� 2004-08-11 CN disclosed
US-20040068002-A1 4-aminobenzopyran derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-08 US disclosed
EP-0412760-B1 Benzopyran derivatives BEECHAM GROUP PLC (GB) 1994-11-23 EP disclosed
EP-0566567-A1 ANTIHYPERTENSIVE BENZOPYRAN DERIVATIVES AMERICAN HOME PRODUCTS CORPORATION (US) 1993-10-27 EP disclosed
EP-0412760-A2 Benzopyran derivatives Beecham Group p.l.c. (GB) 1991-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040068002-A1 4-aminobenzopyran derivatives CYP2D6, KCNH1, CYP2B6 PKM 1437/4885TSHR 2947/4885LMNA 2906/4885
US-10329256-B2 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors KDM1B, KDM1A, KDM2A PKM 920/4885TSHR 4274/4885LMNA 2909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.