Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 3/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20255261 | 0.85 | L3MBTL1 (0.49) | PANK3GPR119HRH3OGA | |
| SCHEMBL20037519 | 0.82 | MAP4K4 (0.49) | PANK3OGA | |
| SCHEMBL20249437 | 0.82 | GPR119 (0.45) | PANK3GPR119HRH3AAK1DGAT1 | |
| SCHEMBL16427561 | 0.81 | GPR119 (0.57) | GPR119 | |
| SCHEMBL20037518 | 0.80 | BPTF (0.56) | OGA | |
| SCHEMBL3827722 | 0.78 | KDM4E (0.43) | PANK3OGA | |
| SCHEMBL3301419 | 0.77 | CKS1B (0.54) | GPR119 | |
| SCHEMBL20255262 | 0.73 | OGA (0.58) | HRH3OGA | |
| SCHEMBL20037669 | 0.73 | PANK3 (0.48) | PANK3 | |
| SCHEMBL28903886 | 0.72 | AAK1 (0.62) | GPR119AAK1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |