Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3827722 | 0.85 | KDM4E (0.43) | BPTFALDH1A1HSD17B10L3MBTL1KDM4E | |
| SCHEMBL20255261 | 0.83 | L3MBTL1 (0.49) | BPTFALDH1A1HSD17B10L3MBTL1KDM4E | |
| SCHEMBL20037519 | 0.83 | MAP4K4 (0.49) | BPTFMAP4K4ALDH1A1OGASMO | |
| SCHEMBL20255223 | 0.82 | BPTF (0.60) | BPTFAOC3MAP4K4DPP4CASP6 | |
| SCHEMBL2068254 | 0.81 | PANK3 (0.59) | BPTFALDH1A1MEN1KMT2A | |
| SCHEMBL16427561 | 0.80 | GPR119 (0.57) | MAP4K4ALDH1A1CKS1BSKP1SKP2 | |
| SCHEMBL20037669 | 0.80 | PANK3 (0.48) | ALDH1A1HSD17B10GAAL3MBTL1KDM4E | |
| SCHEMBL20037531 | 0.80 | PANK3 (0.46) | OGA | |
| SCHEMBL24620129 | 0.79 | BPTF (0.54) | BPTFAOC3MAP4K4DPP4CASP6 | |
| SCHEMBL20249445 | 0.78 | BPTF (0.56) | BPTFAOC3MAP4K4DPP4CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |