Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CTSE | P14091 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20255183 | 0.90 | USP30 (0.42) | NR1H2ALOX5APFEN1SMN1; SMN2RAB9A | |
| SCHEMBL18291721 | 0.78 | ALOX5AP (0.40) | NR1H2ALOX5APFEN1SMN1; SMN2MAPT | |
| SCHEMBL18291496 | 0.78 | USP30 (0.53) | SMN1; SMN2MAPTMEN1TSHRKMT2A | |
| SCHEMBL30484801 | 0.77 | EGLN2 (0.46) | ALOX5APFEN1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL611746 | 0.77 | EGLN2 (0.46) | ALOX5APFEN1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL29741868 | 0.76 | GPR119 (0.50) | NR1H2ALOX5APFEN1SMN1; SMN2MAPT | |
| SCHEMBL29491152 | 0.76 | MAPT (0.44) | NR1H2SMN1; SMN2MAPTMEN1TSHR | |
| SCHEMBL255485 | 0.76 | MAPT (0.44) | NR1H2SMN1; SMN2MAPTMEN1TSHR | |
| SCHEMBL2300710 | 0.75 | HRH3 (0.54) | ALOX5APFEN1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL2301444 | 0.75 | ITGB3 (0.50) | SMN1; SMN2MAPTMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |