Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22663453 | 0.84 | CSF1R (0.41) | CSF1RGLSAXLMERTKCDK4 | |
| SCHEMBL20037642 | 0.80 | SLC6A2 (0.32) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL23768327 | 0.75 | LRRK2 (0.37) | CSF1R | |
| SCHEMBL18291279 | 0.73 | SLC6A4 (0.37) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL20249274 | 0.73 | SLC6A2 (0.37) | SLC6A2SLC6A3SLC6A4HTR1ACHRM1 | |
| SCHEMBL31240205 | 0.72 | LMNA (0.46) | — | |
| SCHEMBL3113252 | 0.72 | LMNA (0.46) | — | |
| Hydrochloric Acid SCHEMBL28513109 | 0.70 | LMNA (0.45) | — | |
| SCHEMBL31532572 | 0.70 | SLC6A4 (0.38) | SLC6A2SLC6A3SLC6A4HTR1A | |
| SCHEMBL28680550 | 0.68 | CHRNB2 (0.46) | SLC6A2HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |